منابع مشابه
Apoptosis, Cell Death and Inflammation
ceptors (e.g. members of the TNF superfamily such as TNFR1, CD95 or Toll-like receptors [4] ), or the intracellular sensors, nucleotide-binding and oligomerization domain (NOD)-like receptors [5, 6] , all of which can instigate inflammatory responses and modulate the cell’s survival/death balance. NOD-like receptors can assemble into large multiprotein complexes, termed inflammasomes, which can...
متن کاملApoptosis, cell death and inflammation.
ceptors (e.g. members of the TNF superfamily such as TNFR1, CD95 or Toll-like receptors [4] ), or the intracellular sensors, nucleotide-binding and oligomerization domain (NOD)-like receptors [5, 6] , all of which can instigate inflammatory responses and modulate the cell’s survival/death balance. NOD-like receptors can assemble into large multiprotein complexes, termed inflammasomes, which can...
متن کاملHost Responses to Group A Streptococcus: Cell Death and Inflammation
Infections caused by group A Streptococcus (GAS) are characterized by robust inflammatory responses and can rapidly lead to life-threatening disease manifestations. However, host mechanisms that respond to GAS, which may influence disease pathology, are understudied. Recent works indicate that GAS infection is recognized by multiple extracellular and intracellular receptors and activates cell s...
متن کاملNanotoxicity: An Interplay of Oxidative Stress, Inflammation and Cell Death
Nanoparticles are emerging as a useful tool for a wide variety of biomedical, consumer and instrumental applications that include drug delivery systems, biosensors and environmental sensors. In particular, nanoparticles have been shown to offer greater specificity with enhanced bioavailability and less detrimental side effects as compared to the existing conventional therapies in nanomedicine. ...
متن کاملInflammatory caspases: key regulators of inflammation and cell death.
The innate immune system represents the first line of defence against infectious agents, and co-ordinates cellular and molecular mechanisms that result in effective inflammatory and anti-microbial responses against pathogens. Infection and cellular stress trigger assembly of canonical and noncanonical inflammasome complexes that activate the inflammatory caspases-1 and -11, respectively. These ...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2009
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2008.11.007